In fascicles twenty-one through twenty-three, The Great Perfection of Wisdom Treatise elaborates on the Buddhist practices of the eight liberations, the eight spheres of mastery, the nine sequential concentrations, the ten universal visualizations, the nine perceptions on the impure, the eight kinds of mindfulness, the ten perceptions, the eleven kinds of wisdom, the three kinds of samadhi, and the three faculties.

In fascicles twenty-four and twenty-five, The Treatise describes in detail the Buddha’s ten powers, four fearlessnesses, and four unobstructed wisdoms.